What's YOur Status? 

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what's happening now ?

Our Tis The Season for Giving Program serves families in the Middle Tennessee area with children age 18 and under.  We provide families with food, gifts, and other essential items depending on their needs. We not only give to the child/children affected by sickle cell disease but to all children, teenagers, and caregivers in the immediate family household, impacted by sickle cell.  The goal is to restore hope and create smiles for families who face challenging physical, emotional and mental stressors that can be brought on by sickle cell disease throughout the year.

Pre-registration is required to participate in the Tis the Season Holiday Party and is open until November 22nd or until program capacity is reached. Please have proof of residency and custody documents available to complete registration.

Register Here

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Let's talk about it- the cure for sickle cell disease. 
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Are you interested in curative treatment for sickle cell disease but you have questions? Want to know the difference between gene therapy with CRISPR-Cas9 technique and gene therapy utilizing a lentiviral vector aka (gene delivery vehicle)?
Check out the recording with Dr. Frangoul because we've got answers.
Dr. Frangoul, is a board-certified pediatric hematologist/oncologist and the medical director of pediatric hematology/oncology for the Sarah Cannon Pediatric Transplant and Cellular Therapy Program at TriStar Centennial. He also serves as an investigator for Sarah Cannon Research Institute, and he serves as the lead investigator for the CRISPR-Cas 9 gene editing trial for sickle cell disease. 

 Replay:
​https://drive.google.com/file/d/1mnEzTCgeACD1xOC5qrFCtJ4H-VIJGl1I/view?usp=drive_link
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​[email protected]
Haydar Frangoul, MD, MS
Program Director
Sarah Cannon Pediatric Hematology/Oncology &
Cellular Therapy @TriStar Centennial
330 23rd Ave North, Suite 450
Nashville, TN 37203
O Office 615-342-7339 F Fax 615-340-4099

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Gene Therapy in Review

Lyfgenia and Casgevy are both one-time gene therapies used to treat sickle cell disease in individuals 12 years of age or older and a history of vaso-occlusive events.

 Learn more. 

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how CASGEVY™ (exagamglogene autotemcel) works

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​BTSSCYCLE Community Impact 

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Donate

Schedule A Blood Donation

WHAT IS ​Sickle Cell Disease (SCD) ? 

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DONATE TODAY .

Make a secure, online, tax deductible donation today.

Donate

SICKLE CELL FACTS.

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What Causes
Sickle Cell Disease

GENETICS. 
SCD is a genetic condition that is present at birth. It is inherited when a child receives two sickle cell genes—one from each parent.

Symptoms and Treatment 


People with sickle cell disease can start to have signs of the disease during the first year of life, usually around 5 months of age. Pain is the hallmark sign of sickle cell disease.
​Symptoms and complications of SCD are different for each person and can range from mild to severe. 

Cure
Is There A Cure

Yes! A blood or marrow transplant  is the only known cure for SCD. Bone marrow is a soft, fatty tissue inside the center of the bones where blood cells are made. A bone marrow or stem cell transplant is a procedure that takes healthy cells that form blood from one person—the donor—and puts them into someone whose bone marrow is not working properly.

Sickle Cell Trait
Sickle cell trait is an inherited blood disorder that affects 1 million to 3 million Americans and 8 to 10 percent of African Americans. Sickle cell trait can also affect Hispanics, South Asians, Caucasians from southern Europe, and people from Middle Eastern countries. More than 100 million people worldwide have sickle cell trait.

Genetic Blood Disorder
Unlike sickle cell disease, a serious illness in which patients have two genes that cause the production of abnormal hemoglobin (the substance in red blood cells that helps carry oxygen), individuals with sickle cell trait carry only one defective gene, have normal functioning hemoglobin and typically live normal lives.

Newborn Testing
All newborns in the United States are now tested for sickle cell disease and sickle cell trait. Sickle cell disease can be identified before birth by testing a sample of amniotic fluid or tissue from the placenta. People who carry the sickle cell gene can seek genetic counseling before pregnancy to discuss options.

​DIAGNOSIS.

SCT is diagnosed with a simple blood test. People at risk of having SCT can talk with a doctor or health clinic about getting this test.

COMPLICATIONS.

Most people with SCT do not have any symptoms of SCD, although—in rare cases—people with SCT might experience complications of SCD, such as pain crises.